President Juan Carlos Varela toured the province to check on the progress of infrastructure and water works.
Projects will benefit the city of Campo Alegre and most resources will be used to improve sanitation.
The plan involves the participation of different government entities, including state water utility Enacal, national environment ministry Marena, the national system for disaster prevention (Sinapred) and the country's municipal governments, among others.
The cities ministry has released around US$20mn to finance sanitation projects in three cities in Espírito Santo state.
The company is looking to reduce debt delinquency rates.
The first stage of the project, which will last four years, will be applied across 55 municipalities and is expected to benefit 1.6mn residents.
The initiative entails the construction of a potable water plant, installation of distribution networks, household connections and new pumping stations. It is expected to benefit up to 540,000 residents by 2040.